Mammalian Sperm Acrosome Reaction: Where Does It Begin Before Fertilization?
نویسندگان
چکیده
منابع مشابه
Site of the mammalian sperm physiological acrosome reaction.
I n mammals and the many other animals in which fertilization involves the establishment of a penetration path through the egg coat, at the apex of the sperm head lies the acrosome— a membrane-limited organelle that houses a complex of enzymes. For fertilization to occur, spermatozoa must first undergo the acrosome reaction (AR), which involves point fusions between the outer acrosomal and over...
متن کاملProtein kinases in mammalian sperm capacitation and the acrosome reaction.
Binding to the zona pellucida of an egg stimulates the spermatozoon to undergo the acrosome reaction, a process that enables it to penetrate the egg. Before this binding, the spermatozoon undergoes a series of biochemical transformations in the female reproductive tract, collectively called capacitation. Only capacitated spermatozoa can bind to the zona pellucida and undergo the acrosome reacti...
متن کاملMost fertilizing mouse spermatozoa begin their acrosome reaction before contact with the zona pellucida during in vitro fertilization.
To fuse with oocytes, spermatozoa of eutherian mammals must pass through extracellular coats, the cumulus cell layer, and the zona pellucida (ZP). It is generally believed that the acrosome reaction (AR) of spermatozoa, essential for zona penetration and fusion with oocytes, is triggered by sperm contact with the zona pellucida. Therefore, in most previous studies of sperm-oocyte interactions i...
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متن کاملTraditional medicine: Where does it stand?
While earth is becoming a smaller village every day, the rapid population growth and ageing is impeding obvious shifting pattern of disease which in turn is inflecting great economic burden required for fast growing health expenditure particularly in the developing world whose suffering from this particular issue is turning into an inflated almost non-curable disease. The major world population...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2011
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.111.092601